Pancreatic enzyme replacement therapy (PERT) shortage
In the UK, there is a shortage of a type of medicine called pancreatic enzyme replacement therapy (PERT), which some people need to help them digest food properly. This medicine is important for people whose pancreas, an organ in the body, does not produce enough enzymes. Enzymes help the body break down food so it can be used for energy.
The shortage has occurred due to manufacturing issues and difficulties in obtaining the necessary ingredients. This has made it difficult for some people to get the medicine they need. The integrated care board, along with community pharmacies, hospitals and GP practices are working on finding alternative solutions to help patients until the shortage is over. It is predicted that some PERT medicines will not be available until 2026.
The medicines affected by this shortage are:
- Creon® 10,000 and 25,000
- Nutrizym® 22 capsules
- Pancrex V® capsules and powder.
What is being done in NHS south east London to support patients affected by this shortage?
- Providing advice to prescribers in GP practices on alternative brands of PERT or treatments.
- Working with a regional procurement centre to import PERT from other countries, which will increase the availability of PERT to community pharmacies in South East London.
- Working with specialist teams and pharmacy services in hospitals to ensure prescribers in GP practices, and community pharmacies can access the support they need to help the patients they prescribe PERT for.
If you are a patient affected by this shortage who has not been able to get your PERT medicine or a suitable alternative:
- Contact your GP: Ask your GP for a separate prescription for PERT, without any other medications included on it. This can make it easier to get PERT from different pharmacies if your usual one is out of stock.
- Check other pharmacies: Check if your regular pharmacy can source other brands from overseas. If they are unable to source another brand, try other local pharmacies.
- Plan ahead: Submit your prescription requests at least two weeks earlier than usual to give your pharmacy more time to obtain the medication.
- Consult healthcare professionals: If you’re struggling to manage your symptoms without PERT, reach out to your dietitian, GP, or specialist nurse for advice on managing your diet and symptoms.
- Specialist support lines: You can also contact specialist nurses through support lines provided by organisations like Pancreatic Cancer UK for additional guidance. Refer to Position Statement Patients: Appendix 2: Other sources of advice for patients.